Kontakt 2019, 21(4):374-379 | DOI: 10.32725/kont.2019.043

Obstructive sleep apnea syndrome and high-risk pregnancyNursing - Original article

Jana Hudecova1,*, Petr Hosek2, Bretislav Gal3, Ondrej Trcka4, Tomas Kostlivy4, Jaroslav Betka5, Martina Baneckova6, Gabriela Krakorova7
1 Charles University, Faculty of Medicine in Pilsen, Department of Gynaecology and Obstetrics, Charles University in Prague, Pilsen, Czech Republic
2 Charles University in Prague, Faculty of Medicine in Pilsen, Biomedical Center, Pilsen, Czech Republic
3 Masaryk University, Faculty of Medicine, Department of Otorhinolaryngology and Head and Neck Surgery, Brno, Czech Republic
4 Charles University, Faculty of Medicine in Pilsen, Ear, Nose and Throat Department, Pilsen, Czech Republic
5 Charles University in Prague, 1st Faculty of Medicine, Department of Otorhinolaryngology and Head and Neck Surgery, Prague, Czech Republic
6 Charles University, Faculty of Medicine in Pilsen, Department of Pathology, Charles University in Prague, Pilsen, Czech Republic
7 Charles University, Faculty of Medicine Pilsen, Pneumology Department, Pilsen, Czech Republic

Introduction: According to the available data, OSAS (Obstructive Sleep Apnea Syndrome) occurs in the fourth decade in 1 to 5% of women in the total population, and over 90% of women with OSAS do not know about their problems. Approximately 15% of obese pregnant females are thought to suffer from SAS. The aim of this work is to explore OSAS incidence in high-risk pregnant women and the association of OSAS with risk factors for pregnancy.

Material: 85 women of a group of 480 monitored high-risk pregnant females were examined, and 61 of these were involved in this study.

Methods: We statistically evaluated the relation between OSAS and hypertension, obesity, preeclamptic placental changes, low pH values of umbilical cord blood, and low PlGF levels in the group of high-risk pregnant women with AHI < 5 and in the group with AHI ≥ 5.

Results: In the monitored group there was a statistical significant coherence between OSAS and gestational diabetes and obesity in high-risk gravid women. Surprisingly, an association with hypertension was not found. From a statistical point of view, evaluations of histomorphological preeclamptic placental changes, low pH values of umbilical cord blood and low PlGF levels was not significant for a small number of respondents with these disorders.

Keywords: High-risk pregnancy; Hypertension; Obesity; OSAS; Preeclampsie

Received: February 8, 2019; Accepted: August 21, 2019; Prepublished online: October 3, 2019; Published: December 13, 2019  Show citation

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Hudecova J, Hosek P, Gal B, Trcka O, Kostlivy T, Betka J, et al.. Obstructive sleep apnea syndrome and high-risk pregnancy. Kontakt. 2019;21(4):374-379. doi: 10.32725/kont.2019.043.
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