Kontakt 2013, 15(2):203-208 | DOI: 10.32725/kont.2013.024

Effect of therapeutic laser on the concentration of cytokines in blood serum in vivo (pilot study)Biomedicine - Original article

Yulia Efremova^1,*, Leoš Navrátil¹, Jaroslav Racek²

¹ České vysoké učení technické v Praze, Fakulta biomedicínského inženýrství, katedra lékařských a humanitních oborů, Kladno

² Univerzita Karlova v Praze, Fakultní nemocnice v Plzni, Ústav klinické biochemie a hematologie

Cytokines are pleiotropeous molecules and perform decisive roles in starting of immune reaction, haematopoiesis processes, neurogenesis etc. Interleucines, growth factors, factors of tumour necrosis and interferons belong among known cytokines. Literary sources document that interleukin-1ß (IL-1ß), interleukin-2 (IL-2), interleukin-6 (IL-6) and the factor of tumour necrosis α (TNF-α) are closely connected and play role at inflammation as well as pain. At present the low - efficient laser therapy is a wide - spread and effective physiotherapy method widely used during rehabilitation of patients with problems of movement. The basic idea of the experiment has been the assessment of changes of concentration of cytokines in the blood serum after laser therapy. We do not know that there would be a thesis concerning changes of concentration of cytokines in the ill with the diagnosis of vertebrogenic algic syndrome (VAS) and the application of a low - efficient laser. 28 probands divided into 3 groups (the first group was treated by laser, the second one - "placebo laser" and the third one was a control one) have been assessed because of changes of the mentioned cytokines and the values of C-reactive protein, rheumatological factor and iron in protoplasm. We have found out that the therapeutic laser influences neither the concentrations of inflammatory cytokines in blood serum of patients with VAS nor the values of C-reactive protein, rheumatological factor and iron.

Keywords: therapeutic laser; interleukin; factor of tumour necrosis; vertebrogenic algic syndrome

Received: September 12, 2012; Accepted: February 5, 2013; Published: June 18, 2013  Show citation